LYSOLIPIDS ARE PROMINENT IN SUBRETINAL DRUSENOID DEPOSITS, A HIGH-RISK PHENOTYPE IN AGE-RELATED MACULAR DEGENERATION

Lysolipids are prominent in subretinal drusenoid deposits, a high-risk phenotype in age-related macular degeneration

IntroductionAge related macular degeneration (AMD) causes legal blindness worldwide, with few therapeutic targets in early disease and no treatments for 80% of cases.Extracellular deposits, including drusen and subretinal drusenoid deposits (SDD; also called reticular pseudodrusen), disrupt cone and rod photoreceptor functions and strongly confer r

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Control and accountability in supply chain management: Evidence from a South African metropolitan municipality

Accountability requires supply chain management (SCM) public officials to account for, report on, explain and justify activities, and accept responsibility for municipal financial expenditure outcomes.Regardless of having SCM systems in place, efficiency in terms of procuring, tendering and sourcing goods and services in South African municipalitie

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The Effect of Mass Incarceration on Criminality in Colombia

This study surveyed the literature on the expected and unexpected effects of incarceration before (deterrence), during (incapacitation), and after (after-effects) prison confinement occurs, through a Fridge Hinge End selective search that favored the analysis of studies with an empirical focus in the national and comparative literature.Then, based

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